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RXRG Antibody

Product Specifications

Background

This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the antiproliferative effects of retinoic acid (RA) . This receptor forms dimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene is expressed at significantly lower levels in non-small cell lung cancer cells. Alternatively spliced transcript variants have been described.

NCBI Gene ID

6258

Swiss Prot

P48443

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-137 of human RXRG (NP_008848.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction, Transcription

Purification

Affinity purification

Positive Control

Jurkat

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 61kDa

Fragment

IgG

Symbol

RXRG

Positive Control 2

DU145

Positive Control 3

U-87MG

Positive Control 4

Mouse brain

Positive Control 5

Rat brain

NCBI Official Name

Retinoid X receptor, gamma

NCBI Organism

Homo sapiens

Other Product Names

RXRG, RXRC, NR2B3

Tested Applications

WB, IHC

Physical Properties

Liquid

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