ACADM Antibody
Product Specifications
Background
This gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
34
Swiss Prot
P11310
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human ACADM (NP_000007.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
Affinity purification
Positive Control
HT-29
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 46kDa
Fragment
IgG
Symbol
ACADM
Positive Control 2
HepG2
Positive Control 3
U-251MG
Positive Control 4
K-562
Positive Control 5
Mouse liver
Positive Control 6
Mouse kidney
NCBI Official Name
Acyl-CoA dehydrogenase, C-4 to C-12 straight chain
NCBI Organism
Homo sapiens
Other Product Names
ACADM, ACAD1, MCAD, MCADH
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
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