LIG1 Antibody
Product Specifications
Background
This gene encodes a member of the ATP-dependent DNA ligase protein family. The encoded protein functions in DNA replication, recombination, and the base excision repair process. Mutations in this gene that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents. Disruption of this gene may also be associated with a variety of cancers. Alternative splicing results in multiple transcript variants.
NCBI Gene ID
3978
Swiss Prot
P18858
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 565-790 of human LIG1 (NP_000225.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Affinity purification
Positive Control
MCF7
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 140kDa
Fragment
IgG
Symbol
LIG1
Positive Control 2
A-549
Positive Control 3
K-562
Positive Control 4
Jurkat
Positive Control 5
22Rv1
Positive Control 6
Mouse testis
NCBI Official Name
Ligase I, DNA, ATP-dependent
NCBI Organism
Homo sapiens
Other Product Names
LIG1, MGC117397, MGC130025
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
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