HSD3B2 Antibody
Product Specifications
Background
The protein encoded by this gene is a bifunctional enzyme that catalyzes the oxidative conversion of delta (5) -ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. It plays a crucial role in the biosynthesis of all classes of hormonal steroids. This gene is predominantly expressed in the adrenals and the gonads. Mutations in this gene are associated with 3-beta-hydroxysteroid dehydrogenase, type II, deficiency. Alternatively spliced transcript variants have been found for this gene.
NCBI Gene ID
3284
Swiss Prot
P26439
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-287 of human HSD3B2 (NP_000189.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Affinity purification
Positive Control
BT-474
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 47kDa
Fragment
IgG
Symbol
HSD3B2
Positive Control 2
U-937
Positive Control 3
COS1
Positive Control 4
COS-2
Positive Control 5
Mouse brain
NCBI Official Name
Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
NCBI Organism
Homo sapiens
Other Product Names
HSD3B2, HSDB, HSDB3, HSD3B, SDR11E2
Tested Applications
WB, IF
Physical Properties
Liquid
Curated Selection
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