PURB Antibody
Product Specifications
Background
This gene product is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia.
NCBI Gene ID
5814
Swiss Prot
Q96QR8
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant protein of human PURB.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Affinity purification
Positive Control
LO2
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 38kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
PURB
Positive Control 2
HeLa
NCBI Official Name
Purine rich element binding protein B
NCBI Organism
Homo sapiens
Other Product Names
PURBETA, transcriptional activator protein Pur-beta
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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