TUBB3 Antibody [5D5D2]

Product Specifications

Background

This gene encodes a class III member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is primarily expressed in neurons and may be involved in neurogenesis and axon guidance and maintenance. Mutations in this gene are the cause of congenital fibrosis of the extraocular muscles type 3. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 6.

NCBI Gene ID

10381

Swiss Prot

Q13509

Host

Mouse

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human TUBB3.

Clonality

Monoclonal

Clone

[5D5D2]

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Neuroscience, Signal Transduction

Purification

Affinity purification

Positive Control

SH-SY5Y

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 55kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

TUBB3

Positive Control 2

MCF7

Positive Control 3

HeLa

Positive Control 4

293T

Positive Control 5

Mouse testis

Positive Control 6

Mouse eye

NCBI Official Name

Tubulin, beta 3 class III

NCBI Organism

Homo sapiens

Other Product Names

Beta-4, CDCBM, CFEOM3A, class III beta-tubulin, OTTHUMP00000176846, TUBB3, TUBB4, tubulin beta-3 chain, tubulin beta-4 chain, tubulin beta-III, tubulin, beta 3