TMED10 Antibody, KO Validated

Product Specifications

Background

This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8.

NCBI Gene ID

10972

Swiss Prot

P49755

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 35-190 of human TMED10 (NP_006818.3) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Validation

Antibody is Knockout validated.

Field of Research

Cell Cycle, Neuroscience, Signal Transduction

Purification

Affinity purification

Positive Control

293T

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 21kDa

Fragment

IgG

Symbol

TMED10

NCBI Official Name

Transmembrane emp24-like trafficking protein 10 (yeast)

NCBI Organism

Homo sapiens

Other Product Names

TMP21 Antibody: p23, TMP21, S31I125, Tmp-21-I, S31III125, P24 (DELTA), Transmembrane emp24 domain-containing protein 10, 21 kDa transmembrane-trafficking protein