CYP24A1 Antibody
Product Specifications
Background
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1,25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
1591
Swiss Prot
Q07973
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 36-448 of human CYP24A1 (NP_001122387.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
Affinity purification
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=18-238
Fragment
IgG
Symbol
CYP24A1
NCBI Official Name
Cytochrome P450, family 24, subfamily A, polypeptide 1
NCBI Organism
Homo sapiens
Other Product Names
CYP24A1, P450-CC24, MGC126274, MGC126273, cytochrome P450, subfamily XXIV (vitami, family 24, subfamily A, polypeptide 1, cytochrome P450 family 24 subfamily A polypeptide 1, CYP24, CP24, 24-OHase, 1, 25-@dihydroxyvitamin D3 24-hydroxylase
Tested Applications
IHC, IF
Physical Properties
Liquid
Curated Selection
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