CYP24A1 Antibody

Product Specifications

Background

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1,25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

1591

Swiss Prot

Q07973

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 36-448 of human CYP24A1 (NP_001122387.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

Affinity purification

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Fragment

IgG

Symbol

CYP24A1

NCBI Official Name

Cytochrome P450, family 24, subfamily A, polypeptide 1

NCBI Organism

Homo sapiens

Other Product Names

CYP24A1, P450-CC24, MGC126274, MGC126273, cytochrome P450, subfamily XXIV (vitami, family 24, subfamily A, polypeptide 1, cytochrome P450 family 24 subfamily A polypeptide 1, CYP24, CP24, 24-OHase, 1, 25-@dihydroxyvitamin D3 24-hydroxylase