MAP3K1 Antibody, KO Validated
Product Specifications
Background
The protein encoded by this gene is a serine/threonine kinase and is part of some signal transduction cascades, including the ERK and JNK kinase pathways as well as the NF-kappa-B pathway. The encoded protein is activated by autophosphorylation and requires magnesium as a cofactor in phosphorylating other proteins. This protein has E3 ligase activity conferred by a plant homeodomain (PHD) in its N-terminus and phospho-kinase activity conferred by a kinase domain in its C-terminus.
NCBI Gene ID
4214
Swiss Prot
Q13233
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1400 to the C-terminus of human MAP3K1 (NP_005912.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Validation
Antibody is Knockout validated.
Field of Research
Cancer, Cell Cycle, Immunology, Signal Transduction
Purification
Affinity purification
Positive Control
HeLa
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 164kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
MAP3K1
NCBI Official Name
Mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
NCBI Organism
Homo sapiens
Other Product Names
MAP3K1, MAPKKK1, MEKK, MEKK1, SRXY6, MEKK 1
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
GTR15151379 1 Vial
Lentiviral human MFF shRNA (UAS) - Lentiviral human MFF shRNA (UAS, RFP) (25)
Ask
View Details