AKT2 Antibody [8G3B6], KO Validated
Product Specifications
Background
This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins.
NCBI Gene ID
208
Swiss Prot
P31751
Host
Mouse
Reactivity
Human, Mouse, Rat, Monkey
Immunogen
Recombinant protein of human AKT2
Clonality
Monoclonal
Clone
[8G3B6]
Conjugation
Unconjugated
Type
Primary Antibodies
Validation
Antibody is Knockout validated.
Field of Research
Apoptosis, Cancer, Cell Cycle, Immunology, Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
293T
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=18-206
Calculated Molecular Weight
Observed: 60kDa
Fragment
IgG
Symbol
AKT2
NCBI Official Name
V-akt murine thymoma viral oncogene homolog 2
NCBI Organism
Homo sapiens
Other Product Names
Rac protein kinase beta, Murine thymoma viral (v-akt) homolog-2, RAC-BETA, PRKBB, PKBBETA, HGNC:392, v-akt murine thymoma viral oncogene homolog 2, AKT2, PKBB, HIHGHH
Tested Applications
WB, IHC, ICC, IF, IP, ChIP
Physical Properties
Liquid
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