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TDP2 Antibody, KO Validated

Product Specifications

Background

This gene encodes a member of a superfamily of divalent cation-dependent phosphodiesterases. The encoded protein associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor associated factors (TRAFs), and inhibits nuclear factor-kappa-B activation. This protein has sequence and structural similarities with APE1 endonuclease, which is involved in both DNA repair and the activation of transcription factors.

NCBI Gene ID

51567

Swiss Prot

O95551

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human TDP2 (NP_057698.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Validation

Antibody is Knockout validated.

Field of Research

Cancer, Transcription

Purification

Affinity purification

Positive Control

HeLa

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=18-204

Calculated Molecular Weight

Observed: 41kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

TDP2

NCBI Official Name

Tyrosyl-DNA phosphodiesterase 2

NCBI Organism

Homo sapiens

Other Product Names

TTRAP, EAP2, AD022, EAPII, TTRAP, hTDP2, dJ30M3.3, RP1-30M3.3

Tested Applications

WB

Physical Properties

Liquid

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