DDX58 Antibody, KO Validated
Product Specifications
Background
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. This gene encodes a protein containing RNA helicase-DEAD box protein motifs and a caspase recruitment domain (CARD) . It is involved in viral double-stranded (ds) RNA recognition and the regulation of immune response.
NCBI Gene ID
23586
Swiss Prot
O95786
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 830 to the C-terminus of human DDX58 (NP_055129.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Validation
Antibody is Knockout validated.
Field of Research
Immunology
Purification
Affinity purification
Positive Control
A-549
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 102kDa
Fragment
IgG
Symbol
DDX58
NCBI Official Name
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
NCBI Organism
Homo sapiens
Other Product Names
RIG-1 Antibody: RIGI, RIG-I, RLR-1, Probable ATP-dependent RNA helicase DDX58, DEAD box protein 58
Tested Applications
WB, IHC, IF, IP
Physical Properties
Liquid
Curated Selection
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