BAK1 Antibody, KO Validated
Product Specifications
Background
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.
NCBI Gene ID
578
Swiss Prot
Q16611
Host
Rabbit
Reactivity
Human, Rat
Immunogen
A synthetic peptide of human BAK1
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Validation
Antibody is Knockout validated.
Field of Research
Apoptosis, Cell Cycle
Purification
Affinity purification
Positive Control
HeLa
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 25kDa
Fragment
IgG
Symbol
BAK1
NCBI Official Name
BCL2-antagonist/killer 1
NCBI Organism
Homo sapiens
Other Product Names
Bak Antibody: BAK, CDN1, BCL2L7, BAK-LIKE, BAK, Apoptosis regulator BAK, Bcl2-L-7
Tested Applications
WB, IHC
Physical Properties
Liquid
Curated Selection
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