CDK2 Antibody, KO Validated
Product Specifications
Background
This gene encodes a member of a family of serine/threonine protein kinases that participate in cell cycle regulation. The encoded protein is the catalytic subunit of the cyclin-dependent protein kinase complex, which regulates progression through the cell cycle. Activity of this protein is especially critical during the G1 to S phase transition. This protein associates with and regulated by other subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A), and p27Kip1 (CDKN1B) . Alternative splicing results in multiple transcript variants.
NCBI Gene ID
1017
Swiss Prot
P24941
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of human CDK2
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Validation
Antibody is Knockout validated.
Field of Research
Cancer, Cell Cycle, Signal Transduction
Purification
Affinity purification
Positive Control
293T
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=18-187
Calculated Molecular Weight
Observed: 33kDa
Fragment
IgG
Symbol
CDK2
NCBI Official Name
Cyclin-dependent kinase 2
NCBI Organism
Homo sapiens
Other Product Names
CDK2, CDKN2, p33 (CDK2)
Tested Applications
WB, IHC
Physical Properties
Liquid
Curated Selection
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