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DCK Antibody

Product Specifications

Background

Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity.

NCBI Gene ID

1633

Swiss Prot

P27707

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human DCK (NP_000779.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Signal Transduction

Purification

Affinity purification

Positive Control

Raji

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 31kDa

Fragment

IgG

Symbol

DCK

Positive Control 2

293T

Positive Control 3

Mouse liver

Positive Control 4

Mouse brain

Positive Control 5

Rat liver

NCBI Official Name

Deoxycytidine kinase

NCBI Organism

Homo sapiens

Other Product Names

DCK, MGC117410, MGC138632

Tested Applications

WB, IHC, IF

Physical Properties

Liquid

Curated Selection

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