ACVRL1 Antibody
Product Specifications
Background
This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2.
NCBI Gene ID
94
Swiss Prot
P37023
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein of human ACVRL1
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Growth Factors, Signal Transduction
Purification
Affinity purification
Positive Control
SH-SY5Y
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 65kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
ACVRL1
Positive Control 2
HL-60
Positive Control 3
MCF7
Positive Control 4
Jurkat
Positive Control 5
Mouse lung
Positive Control 6
Mouse heart
NCBI Official Name
Activin A receptor type II-like 1
NCBI Organism
Homo sapiens
Other Product Names
ACVRL1, HHT, ALK1, HHT2, ORW2, SKR3, ALK-1, ACVRLK1, activin A receptor type II-like 1, Activin A receptor, type II-like kinase 1
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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