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MRPL41 Antibody

Product Specifications

Background

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the YmL27 ribosomal protein family. [provided by RefSeq, Jul 2008]

NCBI Gene ID

64975

Swiss Prot

Q8IXM3

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-137 of human MRPL41 (NP_115866.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Apoptosis, Cancer, Cell Cycle

Purification

Affinity purification

Positive Control

293T

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 15kDa

Fragment

IgG

Symbol

MRPL41

Positive Control 2

PC-3

Positive Control 3

MCF7

NCBI Official Name

Mitochondrial ribosomal protein L41

NCBI Organism

Homo sapiens

Other Product Names

BMRP, MRP-L27, MRPL27, PIG3, RPML27, 39S ribosomal protein L41, mitochondrial, 39S ribosomal protein L27 homolog, L41mt, MRP-L27 homolog, MRP-L41, bcl-2-interacting mitochondrial ribosomal protein L41, cell proliferation-inducing gene 3 protein, mitochondrial large ribosomal subunit protein mL41, proliferation-inducing gene 3

Tested Applications

WB, IHC, IF

Physical Properties

Liquid

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