PLA2G3 Antibody
Product Specifications
Background
This gene encodes a protein that belongs to the secreted phospholipase A2 family, whose members include the bee venom enzyme. The encoded enzyme functions in lipid metabolism and catalyzes the calcium-dependent hydrolysis of the sn-2 acyl bond of phospholipids to release arachidonic acid and lysophospholipids. This enzyme acts as a negative regulator of ciliogenesis, and may play a role in cancer development by stimulating tumor cell growth and angiogenesis. This gene is associated with oxidative stress, and polymorphisms in this gene are linked to risk for Alzheimer's disease. [provided by RefSeq, Apr 2014]
NCBI Gene ID
50487
Swiss Prot
Q9NZ20
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of Human PLA2G3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Signal Transduction
Purification
Affinity purification
Positive Control
293T
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 57kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
PLA2G3
Positive Control 2
K-562
Positive Control 3
Mouse liver
NCBI Official Name
Phospholipase A2, group III
NCBI Organism
Homo sapiens
Other Product Names
PLA2G3, GIII-SPLA2, Phospholipase A2, group III, SPLA2-III, GIII sPLA2, SPLA2III
Tested Applications
WB
Physical Properties
Liquid
Frequently Asked Questions
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