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NOB1 Antibody

Product Specifications

Background

In yeast, over 200 protein and RNA cofactors are required for ribosome assembly, and these are generally conserved in eukaryotes. These factors orchestrate modification and cleavage of the initial 35S precursor rRNA transcript into the mature 18S, 5.8S, and 25S rRNAs, folding of the rRNA, and binding of ribosomal proteins and 5S RNA. Nob1 is involved in pre-rRNA processing. In a late cytoplasmic processing step, Nob1 cleaves a 20S rRNA intermediate at cleavage site D to produce the mature 18S rRNA (Lamanna and Karbstein, 2009 [PubMed 19706509]) .[supplied by OMIM, Nov 2010]

NCBI Gene ID

28987

Swiss Prot

Q9ULX3

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human NOB1 (NP_054781.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

Affinity purification

Positive Control

BxPC-3

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 47kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

NOB1

Positive Control 2

LO2

Positive Control 3

Rat testis

NCBI Official Name

NIN1/RPN12 binding protein 1 homolog (S. cerevisiae)

NCBI Organism

Homo sapiens

Other Product Names

NOB1, ART-4, MST158, MSTP158, NOB1P, PSMD8BP1

Tested Applications

WB

Physical Properties

Liquid

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