SCNN1B Antibody
Product Specifications
Background
Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the beta subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), and Liddle syndrome.
NCBI Gene ID
6338
Swiss Prot
P51168
Host
Rabbit
Reactivity
Human, Mouse, Monkey
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 406-640 of human SCNN1B (NP_000327.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
293T
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 75kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
SCNN1B
Positive Control 2
LO2
Positive Control 3
Mouse lung
NCBI Official Name
Sodium channel, non-voltage-gated 1, beta subunit
NCBI Organism
Homo sapiens
Other Product Names
SCNN1B, BESC1, ENaCb, SCNEB, ENaCbeta
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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