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EXOC3 Antibody

Product Specifications

Background

The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity. [provided by RefSeq, Jul 2008]

NCBI Gene ID

11336

Swiss Prot

O60645

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 396-745 of human EXOC3 (NP_009208.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

Affinity purification

Positive Control

PC-3

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 87kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

EXOC3

Positive Control 2

U-251MG

Positive Control 3

Mouse brain

Positive Control 4

Mouse lung

Positive Control 5

Rat brain

NCBI Official Name

Exocyst complex component 3

NCBI Organism

Homo sapiens

Other Product Names

EXOC3, SEC6, SEC6L1, Sec6p

Tested Applications

WB

Physical Properties

Liquid

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