SP140 Antibody
Product Specifications
Background
This gene encodes a member of the SP100 family of proteins, which are share common domains including an N-terminal homogeneously staining region domain followed by a SP100/autoimmune regulator/NucP41/P75/deformed epidermal autoregulatory factor domain, a plant homeobox zinc finger, and a bromodomain. The encoded protein is interferon-inducible and is expressed at high levels in the nuclei of leukocytes. Variants of this gene have been associated with multiple sclerosis, Crohn's disease, and chronic lymphocytic leukemia. Alternative splicing results in multiple variants. [provided by RefSeq, Aug 2016]
NCBI Gene ID
11262
Swiss Prot
Q13342
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human SP140 (NP_001265380) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology, Transcription
Purification
Affinity purification
Positive Control
Mouse spleen
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 98kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
SP140
Positive Control 2
Mouse thymus
Positive Control 3
Rat thymus
NCBI Official Name
SP140 nuclear body protein
NCBI Organism
Homo sapiens
Other Product Names
SP140, LYSP100, LYSP100-A, LYSP100-B
Tested Applications
WB
Physical Properties
Liquid
Frequently Asked Questions
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