SF3B4 Antibody
Product Specifications
Background
This gene encodes one of four subunits of the splicing factor 3B. The protein encoded by this gene cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be involved in the assembly of the B, C and E spliceosomal complexes. In addition to RNA-binding activity, this protein interacts directly and highly specifically with subunit 2 of the splicing factor 3B. This protein contains two N-terminal RNA-recognition motifs (RRMs), consistent with the observation that it binds directly to pre-mRNA. [provided by RefSeq, Jul 2008]
NCBI Gene ID
10262
Swiss Prot
Q15427
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human SF3B4 (NP_005841.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Affinity purification
Positive Control
Rat spleen
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 44kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
SF3B4
Positive Control 2
Rat lung
NCBI Official Name
Splicing factor 3b, subunit 4, 49kDa
NCBI Organism
Homo sapiens
Other Product Names
SF3B4, AFD1, Hsh49, SAP49, SF3b49
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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