SIGLEC1 Antibody
Product Specifications
Background
This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a lectin-like adhesion molecule that binds glycoconjugate ligands on cell surfaces in a sialic acid-dependent manner. It is a type I transmembrane protein expressed only by a subpopulation of macrophages and is involved in mediating cell-cell interactions. Alternative splicing produces a transcript variant encoding an isoform that is soluble rather than membrane-bound; however, the full-length nature of this variant has not been determined.
NCBI Gene ID
6614
Swiss Prot
Q9BZZ2
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 50-300 of human SIGLEC1 (NP_075556.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology
Purification
Affinity purification
Positive Control
HepG2
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 200kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
SIGLEC1
NCBI Official Name
Sialic acid binding Ig like lectin 1
NCBI Organism
Homo sapiens
Other Product Names
CD169, SIGLEC-1, SN, sialoadhesin, sialic acid binding Ig-like lectin 1, sialoadhesin, sialic acid-binding immunoglobulin-like lectin 1
Tested Applications
WB
Physical Properties
Liquid
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