PDE6G Antibody
Product Specifications
Background
This gene encodes the gamma subunit of cyclic GMP-phosphodiesterase, which is composed of alpha- and beta- catalytic subunits and two identical, inhibitory gamma subunits. This gene is expressed in rod photoreceptors and functions in the phototransduction signaling cascade. It is also expressed in a variety of other tissues, and has been shown to regulate the c-Src protein kinase and G-protein-coupled receptor kinase 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2009]
NCBI Gene ID
5148
Swiss Prot
P18545
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-87 of human PDE6G (NP_002593.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
Affinity purification
Positive Control
Mouse liver
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 13kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
PDE6G
Positive Control 2
Mouse eye
Positive Control 3
Rat spleen
NCBI Official Name
Phosphodiesterase 6G
NCBI Organism
Homo sapiens
Other Product Names
PDEG, RP57, retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma, GMP-PDE gamma, phosphodiesterase 6G, cGMP-specific, rod, gamma, rod cG-PDE G
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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