NFATC4 Antibody
Product Specifications
Background
This gene encodes a member of the nuclear factor of activated T cells (NFAT) protein family. The encoded protein is part of a DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor stimulation and an inducible nuclear component. NFAT proteins are activated by the calmodulin-dependent phosphatase, calcineurin. The encoded protein plays a role in the inducible expression of cytokine genes in T cells, especially in the induction of interleukin-2 and interleukin-4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
NCBI Gene ID
4776
Swiss Prot
Q14934
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 560-710 of human NFATC4 (NP_004545.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology, Signal Transduction, Transcription
Purification
Affinity purification
Positive Control
SKOV3
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 108kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
NFATC4
Positive Control 2
HepG2
Positive Control 3
A-549
Positive Control 4
Mouse lung
Positive Control 5
Mouse kidney
Positive Control 6
Mouse brain
NCBI Official Name
Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
NCBI Organism
Homo sapiens
Other Product Names
NFATC4, NFAT3, NF-AT3, NF-ATC4
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
