TRPM1 Antibody
Product Specifications
Background
This gene encodes a member of the transient receptor potential melastatin subfamily of transient receptor potential ion channels. The encoded protein is a calcium permeable cation channel that is expressed in melanocytes and may play a role in melanin synthesis. Specific mutations in this gene are the cause autosomal recessive complete congenital stationary night blindness-1C. The expression of this protein is inversely correlated with melanoma aggressiveness and as such it is used as a prognostic marker for melanoma metastasis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2011]
NCBI Gene ID
4308
Swiss Prot
Q7Z4N2
Host
Rabbit
Reactivity
Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1343-1642 of human TRPM1 (NP_001238949.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Neuroscience, Signal Transduction
Purification
Affinity purification
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=16-964
Fragment
IgG
Applications Notes
IHC: 1:50 - 1:100
Symbol
TRPM1
NCBI Official Name
Transient receptor potential cation channel subfamily M member 1
NCBI Organism
Homo sapiens
Other Product Names
CSNB1C, LTRPC1, MLSN1, transient receptor potential cation channel subfamily M member 1, long transient receptor potential channel 1, melastatin-1, transient receptor potential melastatin family
Tested Applications
IHC
Physical Properties
Liquid
Curated Selection
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