TRPM1 Antibody

Product Specifications

Background

This gene encodes a member of the transient receptor potential melastatin subfamily of transient receptor potential ion channels. The encoded protein is a calcium permeable cation channel that is expressed in melanocytes and may play a role in melanin synthesis. Specific mutations in this gene are the cause autosomal recessive complete congenital stationary night blindness-1C. The expression of this protein is inversely correlated with melanoma aggressiveness and as such it is used as a prognostic marker for melanoma metastasis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2011]

NCBI Gene ID

4308

Swiss Prot

Q7Z4N2

Host

Rabbit

Reactivity

Mouse

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1343-1642 of human TRPM1 (NP_001238949.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Neuroscience, Signal Transduction

Purification

Affinity purification

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Fragment

IgG

Applications Notes

IHC: 1:50 - 1:100

Symbol

TRPM1

NCBI Official Name

Transient receptor potential cation channel subfamily M member 1

NCBI Organism

Homo sapiens

Other Product Names

CSNB1C, LTRPC1, MLSN1, transient receptor potential cation channel subfamily M member 1, long transient receptor potential channel 1, melastatin-1, transient receptor potential melastatin family