C1 Inactivator Antibody

Product Specifications

Background

This gene encodes a highly glycosylated plasma protein involved in the regulation of the complement cascade. Its protein inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. Deficiency of this protein is associated with hereditary angioneurotic oedema (HANE) . Alternative splicing results in multiple transcript variants encoding the same isoform.

NCBI Gene ID

710

Swiss Prot

P05155

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 201-500 of human C1 Inactivator (NP_001027466.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology, Innate Immunity

Purification

Affinity purification

Positive Control

DU145

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 60kDa.110kDa

Fragment

IgG

Applications Notes

WB: 1:1000 - 1:2000

Symbol

SERPING1

Positive Control 2

SKOV3

Positive Control 3

HeLa

Positive Control 4

LO2

Positive Control 5

U-251MG

Positive Control 6

Mouse liver

NCBI Official Name

Serpin peptidase inhibitor, clade G (C1 inhibitor), member 1

NCBI Organism

Homo sapiens

Other Product Names

SERPING1, C1-inhibiting factor, C1IN, C1 Inh, C1-INH, C1INH, C1NH, C1 Inhibitor, HAE1, HAE2, Plasma protease C1 inhibitor, C1 esterase inhibitor, Serpin G1