IFNAR1 Antibody

Product Specifications

Background

The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The encoded protein also functions as an antiviral factor.

NCBI Gene ID

3454

Swiss Prot

P17181

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 28-290 of human IFNAR1 (NP_000620.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Chemokines & Cytokines, Immunology, Innate Immunity, Signal Transduction, Inflammasomes

Purification

Affinity purification

Positive Control

SW480

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 70kDa

Fragment

IgG

Symbol

IFNAR1

Positive Control 2

K562

NCBI Official Name

Interferon (alpha, beta and omega) receptor 1

NCBI Organism

Homo sapiens

Other Product Names

IFNAR1, interferon (alpha, beta and omega) receptor 1, AVP, IFN-alpha-REC, IFNAR, IFNBR, IFRC, CRF2-1, IFN-R-1, IFN-alpha/beta receptor 1, alpha-type antiviral protein, beta-type antiviral protein, cytokine receptor class-II member 1, cytokine receptor fa