P2RY12 Antibody

Product Specifications

Background

The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelet aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Mutations in this gene are implicated in bleeding disorder, platelet type 8 (BDPLT8) . Alternative splicing results in multiple transcript variants of this gene.

NCBI Gene ID

64805

Swiss Prot

Q9H244

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 200 to the C-terminus of human P2RY12 (NP_795345.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Signal Transduction

Purification

Affinity purification

Positive Control

U-251MG

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 50kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

P2RY12

Positive Control 2

HepG2

Positive Control 3

PC-12

Positive Control 4

DU145

Positive Control 5

Mouse brain

Positive Control 6

Rat testis

NCBI Official Name

Purinergic receptor P2Y12

NCBI Organism

Homo sapiens

Other Product Names

ADPG-R, BDPLT8, HORK3, P2T (AC), P2Y (12) R, P2Y (AC), P2Y (ADP), P2Y (cyc), P2Y12, SP1999, P2Y purinoceptor 12, ADP-glucose receptor, G-protein coupled receptor SP1999, Gi-coupled ADP receptor HORK3, P2Y12 platelet ADP receptor, purinergic receptor P2RY12, purinergic receptor P2Y, G-protein coupled, 12, putative G-protein coupled receptor