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MAML1 Antibody

Product Specifications

Background

This protein is the human homolog of mastermind, a Drosophila protein that plays a role in the Notch signaling pathway involved in cell-fate determination. There is in vitro evidence that the human homolog forms a complex with the intracellular portion of human Notch receptors and can increase expression of a Notch-induced gene. This evidence supports its proposed function as a transcriptional co-activator in the Notch signaling pathway.

NCBI Gene ID

9794

Swiss Prot

Q92585

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human MAML1 (NP_055572.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Signal Transduction, Stem Cell

Purification

Affinity purification

Positive Control

HeLa

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 120kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

MAML1

Positive Control 2

Jurkat

Positive Control 3

Mouse brain

Positive Control 4

Rat brain

NCBI Official Name

Mastermind-like 1 (Drosophila)

NCBI Organism

Homo sapiens

Other Product Names

MAML1, mastermind-like 1 (Drosophila), Mam1, Mam-1, KIAA0200

Tested Applications

WB

Physical Properties

Liquid

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