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TYR Antibody

Product Specifications

Background

The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene.

NCBI Gene ID

7299

Swiss Prot

P14679

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Recombinant protein of human TYR.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

Affinity purification

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Fragment

IgG

Symbol

TYR

NCBI Official Name

Tyrosinase

NCBI Organism

Homo sapiens

Other Product Names

TYR, OCA1A, OCAIA, ATN, CMM8, OCA1, SHEP3

Tested Applications

WB, IHC, IF, IP

Physical Properties

Liquid

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