CD86 Antibody
Product Specifications
Background
This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.
NCBI Gene ID
942
Swiss Prot
P42081
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein of human CD86.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology, Stem Cell
Purification
Affinity purification
Positive Control
Raji
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=16-756
Calculated Molecular Weight
Observed: 80kDa
Fragment
IgG
Symbol
CD86
Positive Control 2
Jurkat
Positive Control 3
HeLa
Positive Control 4
Mouse thymus
Positive Control 5
Mouse spleen
Positive Control 6
Mouse kidney
NCBI Official Name
CD86 molecule
NCBI Organism
Homo sapiens
Other Product Names
CD86 Antibody: CD86 molecule, B70, B7-2, B7.2, LAB72, CD28LG2
Tested Applications
WB, IF, IP
Physical Properties
Liquid
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