CHRNA3 Antibody
Product Specifications
Background
This locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described.
NCBI Gene ID
1136
Swiss Prot
P32297
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 32-240 of human CHRNA3 (NP_000734.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
Affinity purification
Positive Control
SH-SY5Y
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 57kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
CHRNA3
Positive Control 2
HepG2
Positive Control 3
Mouse brain
Positive Control 4
Rat liver
NCBI Official Name
Cholinergic receptor, nicotinic, alpha 3 (neuronal)
NCBI Organism
Homo sapiens
Other Product Names
CHRNA3, LNCR2, PAOD2, NACHRA3
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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