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ABCA2 Antibody

Product Specifications

Background

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White) . This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is highly expressed in brain tissue and may play a role in macrophage lipid metabolism and neural development. Two transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

20

Swiss Prot

Q9BZC7

Host

Rabbit

Reactivity

Mouse

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 2307-2466 of human ABCA2 (NP_997698.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Immunology, Innate Immunity, Neuroscience, Signal Transduction

Purification

Affinity purification

Positive Control

Mouse brain

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 270kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:1000

Symbol

ABCA2

NCBI Official Name

ATP-binding cassette, sub-family A (ABC1), member 2

NCBI Organism

Homo sapiens

Other Product Names

ABCA2, ATP-binding cassette, sub-family A (ABC1), member 2, ABC2, MGC129761, sub-family A, OTTHUMP00000064733, KIAA1062

Tested Applications

WB

Physical Properties

Liquid

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