SELENOM Antibody
Product Specifications
Background
The protein encoded by this gene belongs to the selenoprotein M/SEP15 family. The exact function of this protein is not known. It is localized in the perinuclear region, is highly expressed in the brain, and may be involved in neurodegenerative disorders. Transgenic mice with targeted deletion of this gene exhibit increased weight gain, suggesting a role for this gene in the regulation of body weight and energy metabolism. This protein is a selenoprotein, containing the rare amino acid selenocysteine (Sec) . Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal.
NCBI Gene ID
140606
Swiss Prot
Q8WWX9
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 50-130 of human SELENOM (NP_536355.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Affinity purification
Positive Control
Raji
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 16kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
SELENOM
Positive Control 2
A-431
Positive Control 3
Mouse kidney
Positive Control 4
Mouse heart
Positive Control 5
Mouse brain
NCBI Official Name
Selenoprotein M
NCBI Organism
Homo sapiens
Other Product Names
Selenoprotein M, SelM, SELM, SEPM
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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