P70 S6K Antibody

Product Specifications

Background

This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17.

NCBI Gene ID

6198

Swiss Prot

P23443

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 361-525 of human P70 S6K (NP_003152.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Apoptosis, Cell Cycle, Immunology, Obesity, Signal Transduction

Purification

Affinity purification

Positive Control

HeLa

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 70kDa

Fragment

IgG

Symbol

RPS6KB1

Positive Control 2

293T

Positive Control 3

Jurkat

Positive Control 4

HepG2

Positive Control 5

NIH/3T3

Positive Control 6

Mouse lung

NCBI Official Name

Ribosomal protein S6 kinase, 70kDa, polypeptide 1

NCBI Organism

Homo sapiens

Other Product Names

RPS6KB1, ribosomal protein S6 kinase, 70kD, polypeptide 1, PS6K, S6K, S6K1, STK14A, p70 (S6K) -alpha, p70-S6K, p70-alpha, p70 S6 kinase, alpha 1, alpha 2, serine/threonine kinase 14 alpha