PRKAA1 Antibody
Product Specifications
Background
The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK) . AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
NCBI Gene ID
5562
Swiss Prot
Q13131
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein of human PRKAA1
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Autophagy, Cancer, Cell Cycle, Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
MCF7
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 65kDa
Fragment
IgG
Symbol
PRKAA1
Positive Control 2
Rat liver
NCBI Official Name
Protein kinase, AMP-activated, alpha 1 catalytic subunit
NCBI Organism
Homo sapiens
Other Product Names
PRKAA1, AMPK, AMPKa1, MGC33776, MGC57364
Tested Applications
WB, IHC
Physical Properties
Liquid
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