PTHLH Antibody
Product Specifications
Background
The protein encoded by this gene is a member of the parathyroid hormone family. This hormone, via its receptor, PTHR1, regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. It is responsible for most cases of humoral hypercalcemia of malignancy, and mutations in this gene are associated with brachydactyly type E2 (BDE2) . Alternatively spliced transcript variants have been found for this gene. There is also evidence for alternative translation initiation from non-AUG (CUG and GUG) start sites, downstream of the initiator AUG codon, resulting in nuclear forms of this hormone.
NCBI Gene ID
5744
Swiss Prot
P12272
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 25-175 of human PTHLH (NP_945315.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Growth Factors, Signal Transduction
Purification
Affinity purification
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Fragment
IgG
Applications Notes
IHC: 1:50 - 1:200
Symbol
PTHLH
NCBI Official Name
Parathyroid hormone-like hormone
NCBI Organism
Homo sapiens
Other Product Names
HHM, PLP, BDE2, PTHR, PTHRP, Parathyroid hormone-related protein, Parathyroid hormone-like protein, PTH-rP
Tested Applications
IHC
Physical Properties
Liquid
Curated Selection
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