ARFGEF1 Antibody

Product Specifications

Background

ADP-ribosylation factors (ARFs) play an important role in intracellular vesicular trafficking. The protein encoded by this gene is involved in the activation of ARFs by accelerating replacement of bound GDP with GTP. It contains a Sec7 domain, which may be responsible for guanine-nucleotide exchange activity and also brefeldin A inhibition.

NCBI Gene ID

10565

Swiss Prot

Q9Y6D6

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 220-420 of human ARFGEF1 (NP_006412.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

Affinity purification

Positive Control

U-87MG

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 200kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

ARFGEF1

Positive Control 2

BxPC-3

NCBI Official Name

ADP ribosylation factor guanine nucleotide exchange factor 1

NCBI Organism

Homo sapiens

Other Product Names

ARFGEP1, BIG1, P20brefeldin A-inhibited guanine nucleotide-exchange protein 1, ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited), p200 ARF guanine nucleotide exchange factor