CUL3 Antibody
Product Specifications
Background
This gene encodes a member of the cullin protein family. The encoded protein plays a critical role in the polyubiquitination and subsequent degradation of specific protein substrates as the core component and scaffold protein of an E3 ubiquitin ligase complex. Complexes including the encoded protein may also play a role in late endosome maturation. Mutations in this gene are a cause of type 2E pseudohypoaldosteronism. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
NCBI Gene ID
8452
Swiss Prot
Q13618
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein of human CUL3
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Cancer, Cell Cycle
Purification
Affinity purification
Positive Control
HeLa
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 82kDa, 84kDa
Fragment
IgG
Symbol
CUL3
Positive Control 2
U-251MG
Positive Control 3
Jurkat
Positive Control 4
PC-12
Positive Control 5
Mouse brain
Positive Control 6
Mouse spleen
NCBI Official Name
Cullin 3
NCBI Organism
Homo sapiens
Other Product Names
CUL3, cullin 3, KIAA0617
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
Curated Selection
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