MRPL23 Antibody

Product Specifications

Background

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. The gene is biallelically expressed, despite its location within a region of imprinted genes on chromosome 11.

NCBI Gene ID

6150

Swiss Prot

Q16540

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-153 of human MRPL23 (NP_066957.3) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

Affinity purification

Positive Control

HeLa

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 15kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

MRPL23

Positive Control 2

U-251MG

Positive Control 3

A-549

Positive Control 4

Mouse liver

Positive Control 5

Mouse lung

Positive Control 6

Mouse brain

NCBI Official Name

Mitochondrial ribosomal protein L23

NCBI Organism

Homo sapiens

Other Product Names

L23MRP, RPL23, RPL23L, 39S ribosomal protein L23, mitochondrial, L23 mitochondrial-related protein, L23mt, MRP-L23, mitochondrial large ribosomal subunit protein uL23m, ribosomal protein related to L23 (mitochondrial)