MTIF2 Antibody
Product Specifications
Background
During the initiation of protein biosynthesis, initiation factor-2 (IF-2) promotes the binding of the initiator tRNA to the small subunit of the ribosome in a GTP-dependent manner. Prokaryotic IF-2 is a single polypeptide, while eukaryotic cytoplasmic IF-2 (eIF-2) is a trimeric protein. Bovine liver mitochondria contain IF-2 (mt), an 85-kD monomeric protein that is equivalent to prokaryotic IF-2. The predicted 727-amino acid human protein contains a 29-amino acid presequence. Human IF-2 (mt) shares 32 to 38% amino acid sequence identity with yeast IF-2 (mt) and several prokaryotic IF-2s, with the greatest degree of conservation in the G domains of the proteins.
NCBI Gene ID
4528
Swiss Prot
P46199
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 428-727 of human MTIF2 (NP_002444.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Affinity purification
Positive Control
LO2
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 81kDa
Fragment
IgG
Symbol
MTIF2
Positive Control 2
A-431
Positive Control 3
U-251MG
Positive Control 4
Mouse heart
Positive Control 5
Mouse kidney
Positive Control 6
Mouse liver
NCBI Official Name
Translation initiation factor IF-2, mitochondrial
NCBI Organism
Homo sapiens
Other Product Names
Translation initiation factor IF-2, mitochondrial, IF-2 (Mt), IF-2Mt, IF2 (mt), MTIF2
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
Curated Selection
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