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OLR1 Antibody

Product Specifications

Background

This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.

NCBI Gene ID

4973

Swiss Prot

P78380

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 58-273 of human OLR1 (NP_002534.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer

Purification

Affinity purification

Positive Control

OVCAR3

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 26kDa

Fragment

IgG

Symbol

OLR1

Positive Control 2

HeLa

Positive Control 3

HepG2

NCBI Official Name

Oxidized low density lipoprotein (lectin-like) receptor 1

NCBI Organism

Homo sapiens

Other Product Names

OLR1, CLEC8A, LOX1, SCARE1, LOXIN, SLOX1

Tested Applications

WB, IHC

Physical Properties

Liquid

Frequently Asked Questions

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