CXCR1 Antibody

Product Specifications

Background

The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8) . It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36.

NCBI Gene ID

3577

Swiss Prot

P25024

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 250-350 of human CXCR1 (NP_000625.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Chemokines & Cytokines, Immunology, Innate Immunity, Signal Transduction

Purification

Affinity purification

Positive Control

Rat lung

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 70kDa

Fragment

IgG

Symbol

CXCR1

Positive Control 2

Rat spleen

NCBI Official Name

Chemokine (C-X-C motif) receptor 1

NCBI Organism

Homo sapiens

Other Product Names

IL8RA, interleukin 8 receptor, alpha, interleukin 8 receptor alpha, IL8RBA, IL8R1, IL-8 receptor type 1, CXCR1, CMKAR1, CKR-1, chemokine (C-X-C motif) receptor 1, CDw128a, CD181, CD128, C-C-CKR-1, C-C, IL8RA