STXBP5 Antibody
Product Specifications
Background
Syntaxin 1 is a component of the 7S and 20S SNARE complexes which are involved in docking and fusion of synaptic vesicles with the presynaptic plasma membrane. This gene encodes a syntaxin 1 binding protein. In rat, a similar protein dissociates syntaxin 1 from the Munc18/n-Sec1/rbSec1 complex to form a 10S complex, an intermediate which can be converted to the 7S SNARE complex. Thus this protein is thought to be involved in neurotransmitter release by stimulating SNARE complex formation. Alternatively spliced transcript variants encoding different isoforms have been identified.
NCBI Gene ID
134957
Swiss Prot
Q5T5C0
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 640-900 of human STXBP5 (NP_640337.3) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
Affinity purification
Positive Control
HepG2
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 135kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
STXBP5
NCBI Official Name
Syntaxin binding protein 5
NCBI Organism
Homo sapiens
Other Product Names
LGL3, LLGL3, Nbla0430syntaxin-binding protein 5, lethal (2) giant larvae protein homolog 3, putative protein product of Nbla0430tomosyn, tomosyn-1
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
