SMPD1 / ASM Antibody

Product Specifications

Background

The protein encoded by this gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB) . Multiple transcript variants encoding different isoforms have been identified.

NCBI Gene ID

6609

Swiss Prot

P17405

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human SMPD1 / ASM

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Apoptosis, Cancer, Cell Cycle, Neuroscience, Signal Transduction

Purification

Affinity purification

Positive Control

THP-1

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 60kDa

Fragment

IgG

Symbol

SMPD1

Positive Control 2

HepG2

Positive Control 3

U-251MG

Positive Control 4

MCF-7

Positive Control 5

Mouse brain

Positive Control 6

Mouse liver

NCBI Official Name

Sphingomyelin phosphodiesterase 1, acid lysosomal

NCBI Organism

Homo sapiens

Other Product Names

SMPD1, ASM, NPD, ASMASE

Tested Applications

WB, IF

Physical Properties

Liquid

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