CYP26A1 Antibody

Product Specifications

Background

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein acts on retinoids, including all-trans-retinoic acid (RA), with both 4-hydroxylation and 18-hydroxylation activities. This enzyme regulates the cellular level of retinoic acid which is involved in regulation of gene expression in both embryonic and adult tissues. Two alternatively spliced transcript variants of this gene, which encode the distinct isoforms, have been reported.

NCBI Gene ID

1592

Swiss Prot

O43174

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 50-150 of human CYP26A1 (NP_000774.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

Affinity purification

Positive Control

HepG2

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 55kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

CYP26A1

NCBI Official Name

Cytochrome P450, family 26, subfamily A, polypeptide 1

NCBI Organism

Homo sapiens

Other Product Names

CYP26A1, cytochrome P450, family 26, subfamily A, polypeptide 1, CP26, CYP26, P450RAI, P450RAI1, P450, retinoic acid-inactivating, 1, cytochrome P450, subfamily XXVIA, polypeptide 1, retinoic acid 4-hydroxylase, retinoic acid-metabolizing cytochrome